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The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity.

Id1, a helix-loop-helix (HLH) protein which lacks a DNA binding domain, has been shown to negatively regulate other members of the HLH family by direct protein-protein interactions, both in vitro and in vivo. In this study, we report the results of site-directed mutagenesis experiments aimed at defi...

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Publicado en:Mol Cell Biol
Autores principales: Pesce, S, Benezra, R
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8247002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7874-7880.1993
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