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Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells

Umbilical cord blood (UCB) is an attractive cell source for hematopoietic cell transplantation (HCT). Here we examine whether the combination of homeobox B4 (HOXB4) and Delta-1 ligand (DL) synergize when used together. Monkey and human UCB CD34(+) cells were transduced with a HOXB4-expressing gammar...

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Detalhes bibliográficos
Main Authors: Watts, Korashon L., Delaney, Colleen, Humphries, R. Keith, Bernstein, Irwin D., Kiem, Hans-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031382/
https://ncbi.nlm.nih.gov/pubmed/20921340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-286062
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