Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells

Umbilical cord blood (UCB) is an attractive cell source for hematopoietic cell transplantation (HCT). Here we examine whether the combination of homeobox B4 (HOXB4) and Delta-1 ligand (DL) synergize when used together. Monkey and human UCB CD34(+) cells were transduced with a HOXB4-expressing gammar...

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Bibliografiska uppgifter
Huvudupphovsmän: Watts, Korashon L., Delaney, Colleen, Humphries, R. Keith, Bernstein, Irwin D., Kiem, Hans-Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2010
Ämnen:
Hematopoiesis and Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031382/
https://ncbi.nlm.nih.gov/pubmed/20921340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-286062
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