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Blood stem cell fate regulation by Delta-1–mediated rewiring of IL-6 paracrine signaling
Increasing evidence supports the importance of cell extrinsic regulation in stem cell fate control. Hematopoietic stem cells (HSC) are responsive to local signals from their niche and to systemic feedback from progenitors and mature cells. The Notch ligand Delta-1 (DL1), a key component of the stem...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907753/ https://ncbi.nlm.nih.gov/pubmed/24243972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-520445 |
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