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Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy
Inhibitory antibodies to factor VIII (FVIII) are a major complication in the treatment of hemophilia A, affecting approximately 20% to 30% of patients. Current treatment for inhibitors is based on long-term, daily injections of large amounts of FVIII protein. Liver-directed gene therapy has been use...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031380/ https://ncbi.nlm.nih.gov/pubmed/20876851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288001 |
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