Successful treatment of canine hemophilia by continuous expression of canine FVIIa

Continuous expression of activated factor VII (FVIIa) via gene transfer is a potential therapeutic approach for hemophilia patients with or without inhibitory antibodies to human factor VIII (FVIII) or IX (FIX). Here, we investigate whether gene transfer of an engineered canine FVIIa (cFVIIa) transg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Margaritis, Paris, Roy, Elise, Aljamali, Majed N., Downey, Harre D., Giger, Urs, Zhou, Shangzhen, Merricks, Elizabeth, Dillow, Aaron, Ezban, Mirella, Nichols, Timothy C., High, Katherine A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2009
Gaiak:
Gene Therapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670787/
https://ncbi.nlm.nih.gov/pubmed/19109232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-168377
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