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Successful treatment of canine hemophilia by continuous expression of canine FVIIa

Continuous expression of activated factor VII (FVIIa) via gene transfer is a potential therapeutic approach for hemophilia patients with or without inhibitory antibodies to human factor VIII (FVIII) or IX (FIX). Here, we investigate whether gene transfer of an engineered canine FVIIa (cFVIIa) transg...

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Bibliografske podrobnosti
Main Authors: Margaritis, Paris, Roy, Elise, Aljamali, Majed N., Downey, Harre D., Giger, Urs, Zhou, Shangzhen, Merricks, Elizabeth, Dillow, Aaron, Ezban, Mirella, Nichols, Timothy C., High, Katherine A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670787/
https://ncbi.nlm.nih.gov/pubmed/19109232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-168377
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