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Immature single-positive CD8(+) thymocytes represent the transition from Notch-dependent to Notch-independent T-cell development

Early in T-cell development, cells proceed through stages that are critically dependent on signaling through the Notch receptor. As cells mature, thymocytes transition from being Notch dependent to being Notch independent, but the stage of development during which this transition occurs is unknown....

Полное описание

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Библиографические подробности
Главные авторы: Xiong, Juan, Armato, Michael A., Yankee, Thomas M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031305/
https://ncbi.nlm.nih.gov/pubmed/21148236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq457
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