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Chromosome integrity at a double-strand break requires exonuclease 1 and MRX

The continuity of duplex DNA is generally considered a prerequisite for chromosome continuity. However, as previously shown in yeast as well as human cells, the introduction of a double-strand break (DSB) does not generate a chromosome break (CRB) in yeast or human cells. The transition from DSB to...

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Detalhes bibliográficos
Main Authors: Nakai, Wataru, Westmoreland, Jim, Yeh, Elaine, Bloom, Kerry, Resnick, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031249/
https://ncbi.nlm.nih.gov/pubmed/21115410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.10.004
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