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Characterizing Resection at Random and Unique Chromosome Double-Strand Breaks and Telomere Ends

Resection of DNA double-strand break (DSB) ends, which results in 3′ single-stranded tails, is an early event of DSB repair and can be a critical determinant in choice of repair pathways and eventual genome stability. Current techniques for examining resection are restricted to model in vivo systems...

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Publicat a:Methods Mol Biol
Autors principals: Ma, Wenjian, Westmoreland, Jim, Nakai, Wataru, Malkova, Anna, Resnick, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857595/
https://ncbi.nlm.nih.gov/pubmed/21660686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-129-1_2
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