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Compacted DNA Nanoparticle Gene Transfer of GDNF to the Rat Striatum Enhances the Survival of Grafted Fetal Dopamine Neurons

Previously it was established that infusion of glial cell line-derived neurotrophic factor (GDNF) protein into grafts of embryonic dopamine cells has a neurotrophic effect on the grafted cells. In this study we used a nonviral technique to transfer the gene encoding for GDNF to striatal cells. Plasm...

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Detalhes bibliográficos
Main Authors: Yurek, David M., Flectcher, Anita M., Kowalczyk, Tomasz H., Padegimas, Linas, Cooper, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031110/
https://ncbi.nlm.nih.gov/pubmed/19650971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368909X12483162196881
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