Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: Hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis

Pentalenic acid (1) has been isolated from many Streptomyces species as a co-metabolite of with the sesquiterpenoid antibiotic pentalenolactone and related natural products. We have previously reported the identification of a 13.4-kb gene cluster in the genome of Streptomyces avermitilis implicated...

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Bibliographic Details
Main Authors: Takamatsu, Satoshi, Xu, Lian-Hua, Fushinobu, Shinya, Shoun, Hirofumi, Komatsu, Mamoru, Cane, David E., Ikeda, Haruo
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030646/
https://ncbi.nlm.nih.gov/pubmed/21081950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2010.135
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