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Genome Mining in Streptomyces avermitilis. A Biochemical Baeyer-Villiger Reaction and Discovery of a New Branch of the Pentalenolactone Family Tree

Incubation of 1-deoxy-11-oxopentalenic acid (12) with recombinant PtlE protein from Streptomyces avermitilis in the presence of NADPH and catalytic FAD gave the Baeyer-Villiger oxidation product, the previously unknown compound neopentalenolactone D (13), representing a new branch of the pentalenola...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jiang, Jiaoyang, Tetzlaff, Charles N., Takamatsu, Satoshi, Iwatsuki, Masato, Komatsu, Mamoru, Ikeda, Haruo, Cane, David E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747811/
https://ncbi.nlm.nih.gov/pubmed/19485417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900766w
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