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Total Synthesis of Bryostatin 1

Bryostatin 1 is a marine natural product that is a very promising lead compound due to the potent biological activity it displays against a variety of human disease states. We describe herein the first total synthesis of this agent. The synthetic route adopted is a highly convergent one in which pre...

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Autori principali: Keck, Gary E., Poudel, Yam B., Cummins, Thomas J., Rudra, Arnab, Covel, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030632/
https://ncbi.nlm.nih.gov/pubmed/21175177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110198y
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