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Heterocomplexes of Mannose-binding Lectin and the Pentraxins PTX3 or Serum Amyloid P Component Trigger Cross-activation of the Complement System

The long pentraxin 3 (PTX3), serum amyloid P component (SAP), and C-reactive protein belong to the pentraxin family of pattern recognition molecules involved in tissue homeostasis and innate immunity. They interact with C1q from the classical complement pathway. Whether this also occurs via the anal...

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書誌詳細
主要な著者: Ma, Ying Jie, Doni, Andrea, Skjoedt, Mikkel-Ole, Honoré, Christian, Arendrup, Maiken, Mantovani, Alberto, Garred, Peter
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030347/
https://ncbi.nlm.nih.gov/pubmed/21106539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190637
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