Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

The long pentraxin 3 (PTX3) is a multifunctional soluble pattern recognition molecule that is crucial in innate immune protection against opportunistic fungal pathogens such as Aspergillus fumigatus. The mechanisms that mediate downstream effects of PTX3 are largely unknown. However, PTX3 interacts...

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Autors principals: Ma, Ying Jie, Doni, Andrea, Hummelshøj, Tina, Honoré, Christian, Bastone, Antonio, Mantovani, Alberto, Thielens, Nicole M., Garred, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788878/
https://ncbi.nlm.nih.gov/pubmed/19632990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009225
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