Activation of D1/D5 Dopamine Receptors Protects Neurons from Synapse Dysfunction Induced by Amyloid-β Oligomers

Soluble oligomers of the amyloid-β peptide (AβOs) accumulate in the brains of Alzheimer disease (AD) patients and are implicated in synapse failure and early memory loss in AD. AβOs have been shown to impact synapse function by inhibiting long term potentiation, facilitating the induction of long te...

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Detaylı Bibliyografya
Asıl Yazarlar: Jürgensen, Sofia, Antonio, Leandro L., Mussi, Gabriela E. A., Brito-Moreira, Jordano, Bomfim, Theresa R., De Felice, Fernanda G., Garrido-Sanabria, Emilio R., Cavalheiro, Ésper A., Ferreira, Sergio T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Neurobiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030332/
https://ncbi.nlm.nih.gov/pubmed/21115476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177790
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