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High-pressure EPR reveals conformational equilibria and volumetric properties of spin-labeled proteins

Identifying equilibrium conformational exchange and characterizing conformational substates is essential for elucidating mechanisms of function in proteins. Site-directed spin labeling has previously been employed to detect conformational changes triggered by some event, but verifying conformational...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McCoy, John, Hubbell, Wayne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029758/
https://ncbi.nlm.nih.gov/pubmed/21205903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017877108
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