Llwytho...

Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon

Keratin 8 (K8) is a major intermediate filament protein present in enterocytes and serves an antiapoptotic function in hepatocytes. K8-null mice develop colonic hyperplasia and colitis that are reversed after antibiotic treatment. To investigate the pathways that underlie the mechanism of colonocyte...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Habtezion, Aida, Toivola, Diana M., Asghar, M. Nadeem, Kronmal, Greg S., Brooks, Jacqueline D., Butcher, Eugene C., Omary, M. Bishr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029736/
https://ncbi.nlm.nih.gov/pubmed/21220329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010833108
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