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Reg-II Is an Exocrine Pancreas Injury-Response Product That Is Up-Regulated by Keratin Absence or Mutation

The major keratins in the pancreas and liver are keratins 8 and 18 (K8/K18), but their function seemingly differs in that liver K8/K18 are essential cytoprotective proteins, whereas pancreatic K8/K18 are dispensable. This functional dichotomy raises the hypothesis that K8-null pancreata may undergo...

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Détails bibliographiques
Auteurs principaux: Zhong, Bihui, Strnad, Pavel, Toivola, Diana M., Tao, Guo-Zhong, Ji, Xuhuai, Greenberg, Harry B., Omary, M. Bishr
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096595/
https://ncbi.nlm.nih.gov/pubmed/17898082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0180
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