Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB

The second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP(3)), formed by the p110 family of PI3-kinases, promotes cellular growth, proliferation, and survival, in large part by activating the protein kinase Akt/PKB. We show that inositol polyphosphate multikinase (IPMK) physiologically ge...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maag, David, Maxwell, Micah J., Hardesty, Douglas A., Boucher, Katie L., Choudhari, Namrata, Hanno, Adam G., Ma, Jenny F., Snowman, Adele S., Pietropaoli, Joseph W., Xu, Risheng, Storm, Phillip B., Saiardi, Adolfo, Snyder, Solomon H., Resnick, Adam C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029688/
https://ncbi.nlm.nih.gov/pubmed/21220345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017831108
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