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Estimation of Parent Specific DNA Copy Number in Tumors using High-Density Genotyping Arrays

Chromosomal gains and losses comprise an important type of genetic change in tumors, and can now be assayed using microarray hybridization-based experiments. Most current statistical models for DNA copy number estimate total copy number, which do not distinguish between the underlying quantities of...

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Detalhes bibliográficos
Main Authors: Chen, Hao, Xing, Haipeng, Zhang, Nancy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029233/
https://ncbi.nlm.nih.gov/pubmed/21298078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001060
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