Bayesian estimation of genomic copy number with single nucleotide polymorphism genotyping arrays

BACKGROUND: The identification of copy number aberration in the human genome is an important area in cancer research. We develop a model for determining genomic copy numbers using high-density single nucleotide polymorphism genotyping microarrays. The method is based on a Bayesian spatial normal mix...

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Bibliographic Details
Main Authors: Guo, Beibei, Villagran, Alejandro, Vannucci, Marina, Wang, Jian, Davis, Caleb, Man, Tsz-Kwong, Lau, Ching, Guerra, Rudy
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023756/
https://ncbi.nlm.nih.gov/pubmed/21192799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-350
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