Cell Type-Specific Proteasomal Processing of HIV-1 Gag-p24 Results in an Altered Epitope Repertoire

Proteasomes are critical for the processing of antigens for presentation through the major histocompatibility complex (MHC) class I pathway. HIV-1 Gag protein is a component of several experimental HIV-1 vaccines. Therefore, understanding the processing of HIV-1 Gag protein and the resulting epitope...

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Detalhes bibliográficos
Main Authors: Steers, Nicholas J., Currier, Jeffrey R., Kijak, Gustavo H., di Targiani, Robert C., Saxena, Ashima, Marovich, Mary A., Kim, Jerome H., Michael, Nelson L., Alving, Carl R., Rao, Mangala
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028885/
https://ncbi.nlm.nih.gov/pubmed/21106750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01790-10
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