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Human Immunodeficiency Virus Type 1 Gag p24 Alters the Composition of Immunoproteasomes and Affects Antigen Presentation

Proteasomes are the major source of proteases responsible for the generation of peptides bound to major histocompatibility complex class I molecules. Antigens, adjuvants, and cytokines can modulate the composition and enzymatic activity of proteasomes and thus alter the epitopes generated. In the pr...

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Detalhes bibliográficos
Main Authors: Steers, Nicholas J., Peachman, Kristina K., McClain, Sasha R., Alving, Carl R., Rao, Mangala
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704757/
https://ncbi.nlm.nih.gov/pubmed/19403671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00327-09
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