Correlation between Lethal Toxin-Neutralizing Antibody Titers and Protection from Intranasal Challenge with Bacillus anthracis Ames Strain Spores in Mice after Transcutaneous Immunization with Recombinant Anthrax Protective Antigen

Transcutaneous immunization of mice with recombinant protective antigen (rPA) of Bacillus anthracis resulted in significantly higher lethal toxin-neutralizing antibody titers than did intramuscular injection of alum-adsorbed rPA. Immunized mice were partially protected against intranasal challenge w...

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Autori principali: Peachman, Kristina K., Rao, Mangala, Alving, Carl R., Burge, Robert, Leppla, Stephen H., Rao, Venigalla B., Matyas, Gary R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346607/
https://ncbi.nlm.nih.gov/pubmed/16369043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.794-797.2006
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