Correlation between Lethal Toxin-Neutralizing Antibody Titers and Protection from Intranasal Challenge with Bacillus anthracis Ames Strain Spores in Mice after Transcutaneous Immunization with Recombinant Anthrax Protective Antigen

Transcutaneous immunization of mice with recombinant protective antigen (rPA) of Bacillus anthracis resulted in significantly higher lethal toxin-neutralizing antibody titers than did intramuscular injection of alum-adsorbed rPA. Immunized mice were partially protected against intranasal challenge w...

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Detalhes bibliográficos
Main Authors: Peachman, Kristina K., Rao, Mangala, Alving, Carl R., Burge, Robert, Leppla, Stephen H., Rao, Venigalla B., Matyas, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346607/
https://ncbi.nlm.nih.gov/pubmed/16369043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.794-797.2006
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