Multicomponent Anthrax Toxin Display and Delivery Using Bacteriophage T4

We describe a multicomponent antigen display and delivery system using bacteriophage T4. Two dispensable outer capsid proteins, Hoc (highly antigenic outer capsid protein, 155 copies) and Soc (small outer capsid protein, 810 copies), decorate phage T4 capsid. These proteins bind to the symmetrically...

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Main Authors: Shivachandra, Sathish B., Li, Qin, Peachman, Kristina K., Matyas, Gary R., Leppla, Stephen H., Alving, Carl R., Rao, Mangala, Rao, Venigalla B.
Format: Artigo
Jezik:Inglês
Izdano: 2006
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888565/
https://ncbi.nlm.nih.gov/pubmed/17069938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.10.010
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