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Limited Ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 Polymorphisms To Predict Quinine In Vitro Sensitivity or Clinical Effectiveness in Uganda

Quinine is a standard drug for treating severe malaria in Africa, and it is also increasingly used to treat uncomplicated disease. However, failures of quinine therapy are common, and it is unknown if failures in Africa are due to drug resistance. Recent studies have identified associations between...

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Detalhes bibliográficos
Main Authors: Baliraine, Frederick N., Nsobya, Samuel L., Achan, Jane, Tibenderana, James K., Talisuna, Ambrose O., Greenhouse, Bryan, Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028814/
https://ncbi.nlm.nih.gov/pubmed/21078941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00954-10
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