Polymorphisms of the pfmdr1 but not the pfnhe-1 gene is associated with in vitro quinine sensitivity in Thai isolates of Plasmodium falciparum

BACKGROUND: The emergence of Plasmodium falciparum resistance to most currently used anti-malarial drugs is a major problem in malaria control along the Thai-Myanmar and Thai-Cambodia borders. Quinine (QN) with tetracycline/doxycycline has been used as the second-line treatment for uncomplicated fal...

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Hlavní autoři: Poyomtip, Teera, Suwandittakul, Nantana, Sitthichot, Narumon, Khositnithikul, Rommanee, Tan-ariya, Peerapan, Mungthin, Mathirut
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287963/
https://ncbi.nlm.nih.gov/pubmed/22221394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-7
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