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Resistance-Mediating Plasmodium falciparum pfcrt and pfmdr1 Alleles after Treatment with Artesunate-Amodiaquine in Uganda

Key parasite polymorphisms were assessed in subjects treated for malaria with artesunate-amodiaquine in Tororo, Uganda. For pfcrt, all of the isolates tested had the CVIET haplotype. For pfmdr1, 86Y and 1246Y were common at baseline and their prevalences were significantly higher in new isolates aft...

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Autori principali: Nsobya, Samuel L., Dokomajilar, Christian, Joloba, Moses, Dorsey, Grant, Rosenthal, Philip J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932488/
https://ncbi.nlm.nih.gov/pubmed/17562798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00012-07
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