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Resistance-Mediating Plasmodium falciparum pfcrt and pfmdr1 Alleles after Treatment with Artesunate-Amodiaquine in Uganda

Key parasite polymorphisms were assessed in subjects treated for malaria with artesunate-amodiaquine in Tororo, Uganda. For pfcrt, all of the isolates tested had the CVIET haplotype. For pfmdr1, 86Y and 1246Y were common at baseline and their prevalences were significantly higher in new isolates aft...

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Detalhes bibliográficos
Main Authors: Nsobya, Samuel L., Dokomajilar, Christian, Joloba, Moses, Dorsey, Grant, Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932488/
https://ncbi.nlm.nih.gov/pubmed/17562798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00012-07
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