In Vivo Patterns of Resistance to the HIV Attachment Inhibitor BMS-488043

Attachment inhibitors (AI) are a novel class of HIV-1 antivirals, with little information available on clinical resistance. BMS-488043 is an orally bioavailable AI that binds to gp120 of HIV-1 and abrogates its binding to CD4(+) lymphocytes. A clinical proof-of-concept study of the AI BMS-488043, ad...

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Hlavní autoři: Zhou, Nannan, Nowicka-Sans, Beata, Zhang, Sharon, Fan, Li, Fang, Jie, Fang, Hua, Gong, Yi-Fei, Eggers, Betsy, Langley, David R., Wang, Tao, Kadow, John, Grasela, Dennis, Hanna, George J., Alexander, Louis, Colonno, Richard, Krystal, Mark, Lin, Pin-Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028813/
https://ncbi.nlm.nih.gov/pubmed/21078948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01173-10
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