MicroRNA-27a Regulates Beta Cardiac Myosin Heavy Chain Gene Expression by Targeting Thyroid Hormone Receptor β1 in Neonatal Rat Ventricular Myocytes

MicroRNAs (miRNAs), small noncoding RNAs, are negative regulators of gene expression and play important roles in gene regulation in the heart. To examine the role of miRNAs in the expression of the two isoforms of the cardiac myosin heavy chain (MHC) gene, α- and β-MHC, which regulate cardiac contra...

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Hauptverfasser: Nishi, Hitoo, Ono, Koh, Horie, Takahiro, Nagao, Kazuya, Kinoshita, Minako, Kuwabara, Yasuhide, Watanabe, Shin, Takaya, Tomohide, Tamaki, Yodo, Takanabe-Mori, Rieko, Wada, Hiromichi, Hasegawa, Koji, Iwanaga, Yoshitaka, Kawamura, Teruhisa, Kita, Toru, Kimura, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028640/
https://ncbi.nlm.nih.gov/pubmed/21149577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00581-10
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