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Validating cancer drug targets through chemical genetics
Targeted therapies for cancer promise to revolutionize treatment by specifically inactivating pathways needed for the growth of tumor cells. The most prominent example of such therapy is imatinib (Gleevec), which targets the Bcr-Abl kinase and provides an effective low-toxicity treatment for chronic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028588/ https://ncbi.nlm.nih.gov/pubmed/20708654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2010.08.002 |
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