Combination effects of platinum drugs and N(1), N(11) diethylnorspermine on spermidine/spermine N(1)-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants

PURPOSE: To understand the mechanisms behind platinum drug/DENSPM-induced inhibition of cancer cell growth, we compared the effects of oxaliplatin and cisplatin when combined with DENSPM on the induction of SSAT mRNA, activity, polyamines and cell growth in A2780 human ovarian carcinoma cells and th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tummala, Ramakumar, Diegelman, Paula, Hector, Suzanne, Kramer, Debora L., Clark, Kimberly, Zagst, Patricia, Fetterly, Gerald, Porter, Carl W., Pendyala, Lakshmi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028085/
https://ncbi.nlm.nih.gov/pubmed/20443003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1334-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados