Combination effects of platinum drugs and N(1), N(11) diethylnorspermine on spermidine/spermine N(1)-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants

PURPOSE: To understand the mechanisms behind platinum drug/DENSPM-induced inhibition of cancer cell growth, we compared the effects of oxaliplatin and cisplatin when combined with DENSPM on the induction of SSAT mRNA, activity, polyamines and cell growth in A2780 human ovarian carcinoma cells and th...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Tummala, Ramakumar, Diegelman, Paula, Hector, Suzanne, Kramer, Debora L., Clark, Kimberly, Zagst, Patricia, Fetterly, Gerald, Porter, Carl W., Pendyala, Lakshmi
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2010
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028085/
https://ncbi.nlm.nih.gov/pubmed/20443003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1334-9
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы