Blocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis

AIM: To investigate the anti-tumor effects of nuclear factor-κB (NF-κB) inhibitor SN50 and related mechanisms of SGC7901 human gastric carcinoma cells. METHODS: MTT assay was used to determine the cytotoxic effects of SN50 in gastric cancer cell line SGC7901. Hoechst 33258 staining was used to detec...

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Bibliografiske detaljer
Main Authors: Zhu, Bao-Song, Xing, Chun-Gen, Lin, Fang, Fan, Xiao-Qing, Zhao, Kui, Qin, Zheng-Hong
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Co., Limited 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027014/
https://ncbi.nlm.nih.gov/pubmed/21274377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i4.478
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