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Blocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis
AIM: To investigate the anti-tumor effects of nuclear factor-κB (NF-κB) inhibitor SN50 and related mechanisms of SGC7901 human gastric carcinoma cells. METHODS: MTT assay was used to determine the cytotoxic effects of SN50 in gastric cancer cell line SGC7901. Hoechst 33258 staining was used to detec...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Co., Limited
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3027014/ https://ncbi.nlm.nih.gov/pubmed/21274377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i4.478 |
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