Suppression of IL-12 production by tristetraprolin through blocking NF-κB nuclear translocation

Tristetraprolin (TTP), a mRNA-binding protein, plays a significant role in regulating the expression of adenylate-uridylate-rich elements (AREs) containing messenger RNAs (mRNAs). Mice deficient of TTP (TTP(−/−)) develop a systemic autoimmune inflammatory syndrome characterized by cachexia, conjunct...

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Main Authors: Gu, Ling, Ning, Huan, Qian, Xuesong, Huang, Qi, Hou, Rong, Almouranni, Rajaa, Fu, Mingui, Blackshear, Perry J., Liu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788611/
https://ncbi.nlm.nih.gov/pubmed/23997224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300126
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