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Suppression of IL-12 production by tristetraprolin through blocking NF-κB nuclear translocation
Tristetraprolin (TTP), a mRNA-binding protein, plays a significant role in regulating the expression of adenylate-uridylate-rich elements (AREs) containing messenger RNAs (mRNAs). Mice deficient of TTP (TTP(−/−)) develop a systemic autoimmune inflammatory syndrome characterized by cachexia, conjunct...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788611/ https://ncbi.nlm.nih.gov/pubmed/23997224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300126 |
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