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Oligonucleotide therapeutic approaches for Huntington disease
Huntington disease is an autosomal dominant neurodegenerative disorder caused by a toxic expansion in the CAG repeat region of the huntingtin gene. Oligonucleotide approaches based on RNAi and antisense oligonucleotides provide promising new therapeutic strategies for direct intervention through red...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026739/ https://ncbi.nlm.nih.gov/pubmed/21285523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45130 |
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