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Therapeutic Approaches for Inhibition of Protein Aggregation in Huntington's Disease

Huntington's disease (HD) is a late-onset and progressive neurodegenerative disorder that is caused by aggregation of mutant huntingtin protein which contains expanded-polyglutamine. The molecular chaperones modulate the aggregation in early stage and known for the most potent protector of neur...

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Autors principals: Kim, Sangjune, Kim, Kyong-Tai
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society for Brain and Neural Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984955/
https://ncbi.nlm.nih.gov/pubmed/24737938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2014.23.1.36
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