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Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors

Ethyl alcohol (ethanol) has many molecular targets in the nervous system, its potency at these sites being low compared to those of sedative drugs. This has made it difficult to discover ethanol's binding site(s). There are two putative binding sites at γ-aminobutyric acid (GABA) type A recepto...

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Détails bibliographiques
Auteurs principaux: Linden, Anni-Maija, Schmitt, Ulrich, Leppä, Elli, Wulff, Peer, Wisden, William, Lüddens, Hartmut, Korpi, Esa R.
Format: Artigo
Langue:Inglês
Publié: Frontiers Research Foundation 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026482/
https://ncbi.nlm.nih.gov/pubmed/21270945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2011.00003
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