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Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors

Ethyl alcohol (ethanol) has many molecular targets in the nervous system, its potency at these sites being low compared to those of sedative drugs. This has made it difficult to discover ethanol's binding site(s). There are two putative binding sites at γ-aminobutyric acid (GABA) type A recepto...

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Hlavní autoři: Linden, Anni-Maija, Schmitt, Ulrich, Leppä, Elli, Wulff, Peer, Wisden, William, Lüddens, Hartmut, Korpi, Esa R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026482/
https://ncbi.nlm.nih.gov/pubmed/21270945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2011.00003
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