From synapse to behavior: rapid modulation of defined neuronal types with engineered GABA(A) receptors

In mammals, identifying the contribution of specific neurons or networks to behavior is a key challenge. Here we describe an approach that facilitates this process by enabling the rapid modulation of synaptic inhibition in defined cell populations. Binding of zolpidem, a systemically active alloster...

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Detalhes bibliográficos
Main Authors: Wulff, Peer, Goetz, Thomas, Leppä, Elli, Linden, Anni-Maija, Renzi, Massimiliano, Swinny, Jerome D, Vekovischeva, Olga Y, Sieghart, Werner, Somogyi, Peter, Korpi, Esa R, Farrant, Mark, Wisden, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2092503/
https://ncbi.nlm.nih.gov/pubmed/17572671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1927
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