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High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission

Increased production of reactive oxygen species (ROS) from mitochondria is the main cause of hyperglycemic complications. We previously showed that hyperglycemic conditions induce mitochondrial fragmentation that is causal for ROS overproduction. This study was to identify signaling components that...

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Hlavní autoři: Yu, Tianzheng, Jhun, Bong Sook, Yoon, Yisang
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025178/
https://ncbi.nlm.nih.gov/pubmed/20518702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3284
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