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Glucose Stimulation Induces Dynamic Change of Mitochondrial Morphology to Promote Insulin Secretion in the Insulinoma Cell Line INS-1E

Fission and fusion of mitochondrial tubules are the major processes regulating mitochondrial morphology. However, the physiological significance of mitochondrial shape change is poorly understood. Glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells requires mitochondrial ATP production...

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Detalhes bibliográficos
Main Authors: Jhun, Bong Sook, Lee, Hakjoo, Jin, Zheng-Gen, Yoon, Yisang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614983/
https://ncbi.nlm.nih.gov/pubmed/23565276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060810
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