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High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission

Increased production of reactive oxygen species (ROS) from mitochondria is the main cause of hyperglycemic complications. We previously showed that hyperglycemic conditions induce mitochondrial fragmentation that is causal for ROS overproduction. This study was to identify signaling components that...

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Detalhes bibliográficos
Main Authors: Yu, Tianzheng, Jhun, Bong Sook, Yoon, Yisang
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025178/
https://ncbi.nlm.nih.gov/pubmed/20518702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3284
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