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Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

AIMS: One of the main causes of cardiovascular complications in diabetes is the hyperglycemia-induced cell injury, and mitochondrial fission has been implicated in the apoptotic process. We investigated the role of mitochondrial fission in high glucoseinduced cardiovascular cell injury. METHODS: We...

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Detalhes bibliográficos
Main Authors: Yu, Tianzheng, Sheu, Shey-Shing, Robotham, James L., Yoon, Yisang
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646899/
https://ncbi.nlm.nih.gov/pubmed/18440987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn104
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