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Quercetin, a fluorescent bioflavanoid, inhibits Trypanosoma brucei hexokinase 1
Hexokinases from the African trypanosome, Trypanosoma brucei, are attractive targets for the development of anti-parasitic drugs, in part because the parasite utilizes glycolysis exclusively for ATP production during the mammalian infection. Here, we have demonstrated that the bioflavanoid quercetin...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025057/ https://ncbi.nlm.nih.gov/pubmed/20971104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2010.10.011 |
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