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Quercetin, a fluorescent bioflavanoid, inhibits Trypanosoma brucei hexokinase 1

Hexokinases from the African trypanosome, Trypanosoma brucei, are attractive targets for the development of anti-parasitic drugs, in part because the parasite utilizes glycolysis exclusively for ATP production during the mammalian infection. Here, we have demonstrated that the bioflavanoid quercetin...

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Sonraí Bibleagrafaíochta
Main Authors: Dodson, Heidi C., Lyda, Todd L., Chambers, Jeremy W., Morris, Meredith T., Christensen, Kenneth A., Morris, James C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025057/
https://ncbi.nlm.nih.gov/pubmed/20971104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2010.10.011
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